Wegener K M, Heje N I, Aarestrup F M, Ravn B T, Osterby J
Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
Zentralbl Veterinarmed A. 1993 Jun;40(5):359-70. doi: 10.1111/j.1439-0442.1993.tb00639.x.
The joint cartilage of the head of the radius, the metacarpal bone, the tibial cochlea, the proximal trochlea of the talus and the metatarsal bone of 26 cattle in the age groups fetuses, 0 days, 2-5 weeks, 2-5 months, 7-13 months, 2-3.5 years, and 5-7 years were examined macroscopically and histologically. Synovial grooves developed on all joint surfaces examined, but at different times. At some locations the development of the grooves began prenatally. During the groove development the same features were in principle observed on all joint surfaces: Degeneration and progressive thinning of the joint cartilage, invasion of connective tissue into the cartilage, cessation of the endochondral ossification, and depression of the groove area into the subchondral bone. The findings indicated that the synovial grooves should be considered as being part of the normal morphology of the joints. In 4 animals aged from 3 weeks to 13 months dyschondroplastic (osteochondrotic) lesions were observed in the joint cartilage both inside and outside the groove areas on one or more joint surfaces.
对26头处于胎儿期、0日龄、2 - 5周龄、2 - 5月龄、7 - 13月龄、2 - 3.5岁和5 - 7岁等年龄组的牛的桡骨头、掌骨、胫骨髁、距骨近端滑车和跖骨的关节软骨进行了宏观和组织学检查。在所检查的所有关节表面均出现了滑膜沟，但出现时间不同。在某些部位，沟的发育在产前就已开始。在沟的发育过程中，在所有关节表面原则上观察到相同的特征：关节软骨退变和逐渐变薄、结缔组织侵入软骨、软骨内成骨停止以及沟区向软骨下骨凹陷。这些发现表明，滑膜沟应被视为关节正常形态的一部分。在4只年龄为3周龄至13月龄的动物中，在一个或多个关节表面的沟区内外的关节软骨中观察到了发育异常（骨软骨病）病变。
