Sestoft D, Meden P, Hemmingsen R, Hancke B, Madsen P L, Friberg L
Department of Psychiatry E, Bispebjerg Hospital, Copenhagen, Denmark.
Acta Psychiatr Scand. 1993 Aug;88(2):140-3. doi: 10.1111/j.1600-0447.1993.tb03428.x.
This is a presentation of 2 cases in which the intraictal regional cerebral blood flow distribution was measured with the 99mTc-HMPAO single photon emission computerized tomography technique during an electrically induced seizure. Although the seizure was verified as generalized on electroencephalography, the regional neuronal activity expressed as rCBF unexpectedly was markedly asymmetrical in one of the cases. These findings demonstrated that the 99mTc-HMPAO technique makes it possible to discriminate intraictal variation in cortical and subcortical activation between the hemispheres during electroencephalography-verified generalized seizures.
本文介绍了2例在电诱发癫痫发作期间，采用99mTc-HMPAO单光子发射计算机断层扫描技术测量发作期局部脑血流分布的病例。尽管脑电图证实癫痫发作是全身性的，但在其中1例中，以rCBF表示的局部神经元活动出人意料地明显不对称。这些发现表明，99mTc-HMPAO技术能够在脑电图证实的全身性癫痫发作期间，区分半球间皮质和皮质下激活的发作期变化。
