Reich S D, Wiernik P H
Am J Dis Child. 1976 Aug;130(8):888-9. doi: 10.1001/archpedi.1976.02120090098019.
The leukemias are neoplastic processes that have been associated with a variety of genetic disorders. A case of an adolescent with both acute myelomonocytic leukemia and von Recklinghausen disease is presented, and the literature reviewed to show that these two diseases are associated. Although the number of cases in the literature suggests that in children with von Recklinghausen disease there is a greater risk of leukemia developing, prospective studies are needed to prove this point.
白血病是与多种遗传疾病相关的肿瘤性病变。本文报告了一例同时患有急性粒单核细胞白血病和冯·雷克林霍增氏病的青少年病例，并回顾相关文献以表明这两种疾病之间存在关联。尽管文献中的病例数量表明，患有冯·雷克林霍增氏病的儿童患白血病的风险更高，但仍需要前瞻性研究来证实这一点。
