Waller B F, Johnson D E, Schnitt S J, Pinkerton C A, Simpson J B, Baim D S
Cardiovascular Pathology Registry, St. Vincent Hospital, Indianapolis, Indiana.
Am J Cardiol. 1993 Oct 18;72(13):80E-87E. doi: 10.1016/0002-9149(93)91042-g.
Histologic analysis of atherectomy samples from > 400 patients who received directional coronary atherectomy at 3 separate institutions disclosed 2 major categories of tissue: atherosclerotic plaque (with or without thrombus) and intimal proliferation (hyperplasia, with or without thrombus). The predominant tissue type in atherectomy samples from native, primary, or de novo coronary artery stenoses was atherosclerotic plaque. The predominant tissue type in atherectomy samples from restenosis lesions (prior balloon angioplasty, atherectomy, or both) was intimal proliferation with variable amounts of atherosclerotic plaques (with or without thrombus). Deep vessel wall components (media, adventitia) were identified at varying frequencies. The clinical relevance of atherectomy tissue is reviewed.
对来自3个不同机构接受定向冠状动脉斑块旋切术的400多名患者的斑块旋切术样本进行组织学分析，发现了2大类组织：动脉粥样硬化斑块（有或无血栓）和内膜增生（增生，有或无血栓）。来自天然、原发性或初发冠状动脉狭窄的斑块旋切术样本中的主要组织类型是动脉粥样硬化斑块。来自再狭窄病变（先前球囊血管成形术、斑块旋切术或两者皆有）的斑块旋切术样本中的主要组织类型是内膜增生，并伴有不同数量的动脉粥样硬化斑块（有或无血栓）。不同频率地识别出深部血管壁成分（中膜、外膜）。本文对斑块旋切术组织的临床相关性进行了综述。
