Am J Clin Pathol. 1993 Oct;100(4):371-2. doi: 10.1093/ajcp/100.4.371.
Of the three ethylenediaminetetraacetic acid (EDTA) salts used for anticoagulation of blood specimens for hematologic testing, potassium salts are the most readily soluble. Tripotassium EDTA is dispensed as a liquid and thus causes a slight dilution of the specimen. This salt also has been shown to affect the red blood cell size more at increased concentrations and on storage than the dipotassium salt. Therefore, dipotassium EDTA is recommended as the anticoagulant of choice in specimen collection for blood cell counting and sizing. The amount of dipotassium EDTA used is 1.5-2.2 mg (3.7-5.4 mumol) per milliliter of blood.
在用于血液学检测的血液标本抗凝的三种乙二胺四乙酸（EDTA）盐中，钾盐的溶解度最高。三水合乙二胺四乙酸钾以液体形式分发，因此会对标本造成轻微稀释。研究还表明，与二水合乙二胺四乙酸钾相比，该盐在浓度增加和储存时对红细胞大小的影响更大。因此，推荐使用二水合乙二胺四乙酸钾作为血细胞计数和大小测定标本采集的首选抗凝剂。每毫升血液中二水合乙二胺四乙酸钾的用量为1.5 - 2.2毫克（3.7 - 5.4微摩尔）。
