Wood M, Ellenbogen K, Stambler B
Department of Cardiac Electrophysiology, Medical College of Virginia, Richmond 23298.
Am J Med Sci. 1993 Oct;306(4):241-7. doi: 10.1097/00000441-199310000-00007.
Radiofrequency catheter ablation techniques allow for safe and highly effective curative therapy of a variety of cardiac dysrhythmias. The technique involves the delivery of a high-frequency, alternating electrical current through an intravascular catheter to sites of arrhythmogenic myocardium. This current induces resistive electrical heating of the tissue, resulting in discrete areas of myocardial destruction through coagulation and desiccation. Dysrhythmias most commonly treated with these techniques are atrioventricular nodal reentry and tachycardias related to accessory atrioventricular bypass tracts. For these dysrhythmias, success rates of 90% to 95% are achievable with a low (2% to 4%) risk of complications. Radiofrequency catheter ablation techniques also have been used to treat ventricular tachycardias, atrial flutter, ectopic atrial tachycardia, and sinus node reentry, albeit with lower success rates. These techniques are still evolving, alternate energy sources (such as microwave and laser) and improved catheter technology should enhance the technique's safety and efficacy for a wider range of dysrhythmias.
射频导管消融技术可对多种心律失常进行安全且高效的根治性治疗。该技术是通过血管内导管将高频交流电输送至致心律失常心肌部位。这种电流会引起组织的电阻性电加热,通过凝固和干燥导致心肌离散性破坏。最常采用这些技术治疗的心律失常是房室结折返性心动过速以及与房室旁路相关的心动过速。对于这些心律失常,成功率可达90%至95%,并发症风险较低(2%至4%)。射频导管消融技术也已用于治疗室性心动过速、心房扑动、异位房性心动过速和窦房结折返,尽管成功率较低。这些技术仍在不断发展,替代能源(如微波和激光)以及改进的导管技术应能提高该技术对更广泛心律失常的安全性和有效性。