Geschwind H, Nitenberg A, Magnier S, Laurent D
Arch Mal Coeur Vaiss. 1976 Jul;69(7):711-9.
A haemodynamic and 2-plane cine-angiographic study of 23 patients with obstructive cardiomyopathy has shown that the mitral valve has a limited opening capacity, an unusually anterior position in early systole and is displaced anteriorly during systole. Mitral incompetence is present in more than half of the cases, but usually remains as the only lesion. When it is severe, it is because there are additional lesion: perforation, rupture of the cordae. The behaviour of the mitral valve was fairly constant in all 15 cases of hypertrophic, hyperkinetic, cardiomyopathy, and mitral incompetence was common, and usually found in isolation. The mechanism is discussed, and the physiopathological and therapeutic implications of these facts are reviewed.
对23例梗阻性心肌病患者进行的血流动力学和双平面电影血管造影研究表明,二尖瓣开口能力有限,在收缩早期位置异常靠前,且在收缩期向前移位。超过半数病例存在二尖瓣关闭不全,但通常仅为唯一病变。当二尖瓣关闭不全严重时,是因为存在其他病变:穿孔、腱索断裂。在15例肥厚性、运动亢进性心肌病患者中,二尖瓣的表现相当一致,二尖瓣关闭不全很常见,且通常单独存在。文中讨论了其机制,并对这些事实的生理病理及治疗意义进行了综述。