Sutor B, Heser J L, Rooke T W
Mayo Clinic, Rochester, Minnesota.
Angiology. 1993 Oct;44(10):777-83. doi: 10.1177/000331979304401003.
In 37 patients (69 limbs) referred to Mayo Clinic's Vascular Center for possible venous valvular insufficiency in the lower limb, calf muscle pump function, calf compliance, and venous refilling times were measured by strain gauge plethysmography techniques. Patient limbs were separated into four categories based on 90% refilling time (T90) following fifteen deep knee bends: normal (n = 16), mild/moderate (n = 28), severe (n = 16), and edema of nonvenous origin (n = 9). Pump function was assessed in actual pumping volumes (mL) and in percent pumping volumes (mL/100 mL), and was reduced in all noncontrol categories. Calf compliance was assessed in actual volume change (mL/mmHg) and in percent volume change (mL/100 mL/mmHg) and was increased in the severe reflux category. Ten study patients had 1 normal category limb and 1 reflux category limb. Paired analysis of these limbs showed pump function to be decreased and calf compliance to be increased in the diseased group limbs.
在37例（69条肢体）因可能存在下肢静脉瓣膜功能不全而转诊至梅奥诊所血管中心的患者中，采用应变计体积描记技术测量了小腿肌肉泵功能、小腿顺应性和静脉充盈时间。根据15次深屈膝后的90%充盈时间（T90），将患者肢体分为四类：正常（n = 16）、轻度/中度（n = 28）、重度（n = 16）和非静脉源性水肿（n = 9）。通过实际泵血量（mL）和泵血量百分比（mL/100 mL）评估泵功能，所有非对照组的泵功能均降低。通过实际体积变化（mL/mmHg）和体积变化百分比（mL/100 mL/mmHg）评估小腿顺应性，重度反流组的小腿顺应性增加。10名研究患者有1条正常肢体和1条反流肢体。对这些肢体进行配对分析显示，患病组肢体的泵功能降低，小腿顺应性增加。
