免疫吸附血浆置换治疗重症全身型重症肌无力
Immunoadsorption plasmapheresis for severe generalised myasthenia gravis.
作者信息
Ichikawa M, Koh C S, Hata Y, Tohyama M, Tsuno T, Komiyama A
机构信息
Department of Paediatrics, Shinshu University, School of Medicine, Matsumoto, Japan.
出版信息
Arch Dis Child. 1993 Aug;69(2):236-8. doi: 10.1136/adc.69.2.236.
Two patients with severe generalised myasthenia gravis of childhood were successfully treated with immunoadsorption plasmapheresis. One patient was a 5 year old girl and the other was a 12 year old girl. A dramatic improvement in bulbar symptoms and generalised muscle weakness was achieved without any side effects. Plasma exchange may also yield clinical improvement for myasthenia gravis, but the treatment is accompanied by the risk of viral infections and hypersensitivity reactions. Immunoadsorption plasmapheresis is an effective treatment for severe generalised myasthenia gravis of childhood and is superior to plasma exchange with respect to safety.
两名儿童重症全身性重症肌无力患者通过免疫吸附血浆置换术成功治愈。一名患者是5岁女孩，另一名是12岁女孩。球部症状和全身性肌无力得到显著改善，且无任何副作用。血浆置换对重症肌无力也可能产生临床改善作用，但该治疗伴有病毒感染和过敏反应的风险。免疫吸附血浆置换术是治疗儿童重症全身性重症肌无力的有效方法，在安全性方面优于血浆置换。
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