患病早产儿的早期或晚期肠外营养？
Early or late parenteral nutrition for the sick preterm infant?
作者信息
Brownlee K G, Kelly E J, Ng P C, Kendall-Smith S C, Dear P R
机构信息
St James's University Hospital, Academic Unit of Paediatrics and Child Health, Leeds.
出版信息
Arch Dis Child. 1993 Sep;69(3 Spec No):281-3. doi: 10.1136/adc.69.3_spec_no.281.
Abstract
No one doubts that good nutrition is an important component of neonatal intensive care, nor that this can only be accomplished by the use of intravenous fat. With regard to the effects of nutrition on bronchopulmonary dysplasia, however, we are facing a dilemma. On the one hand there is the suggestion that inadequate nutrition increases the severity of bronchopulmonary dysplasia and on the other that the use of intravenous fat predisposes to it. In an attempt to narrow the area of uncertainty we randomly allocated 129 infants of less than 1750 g birth weight to receive either early or late lipid containing parenteral nutrition. The median duration of ventilation support in the 'early' group was 8.5 days and in the 'late' group eight days; this was not significantly different.
摘要
没有人怀疑良好的营养是新生儿重症监护的重要组成部分，也没有人怀疑这只能通过静脉输注脂肪来实现。然而，关于营养对支气管肺发育不良的影响，我们面临着一个困境。一方面，有观点认为营养不足会增加支气管肺发育不良的严重程度；另一方面，有人认为使用静脉脂肪会诱发这种情况。为了缩小不确定性的范围，我们将129名出生体重低于1750克的婴儿随机分配，分别接受早期或晚期含脂质的肠外营养。“早期”组的通气支持中位持续时间为8.5天，“晚期”组为8天；两者没有显著差异。
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