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[盐酸四咪唑和盐酸左旋咪唑对牛乳房的适应性及其用于牛乳房内注射治疗原圆酵母菌病的用药建议]

[Udder compatibility of tetramisole and levamisole hydrochloride and suggestion for the prescription of their intramammary use in cattle against Prototheca zopfii].

作者信息

Bergmann A

机构信息

Institut für Mikrobiologie und Tierseuchenlehre, Universität Leipzig.

出版信息

Berl Munch Tierarztl Wochenschr. 1993 Aug;106(8):253-6.

PMID:8216186
Abstract

Preparations with 4 percent Tetramisole or Levamisole hydrochloride were compatible in the mammary gland after application up to 40 ml/quarter (4 mg/kg body mass) for up to 6 milking times. 100 ml of the preparations were also clinically compatible in a single quarter (10 mg/kg body mass) on several days. After intramammary application of 30 ml/quarter (3 mg/kg body mass) Prototheca suppressing values in milk serum were evident for at least 6 hours. One application of 200 ml in one quarter has caused Prototheca suppressing values for 36 hours in milk serum up to dilution 1:4. Nilverm given to cattle in high dosage orally did not lead to Prototheca suppressing values in milk sera.

摘要

含4%盐酸四咪唑或盐酸左旋咪唑的制剂,在每季度应用多达40毫升(4毫克/千克体重)、最多挤奶6次后,在乳腺中是相容的。100毫升该制剂在单季度(10毫克/千克体重)连续数天应用时在临床上也是相容的。每季度乳腺内应用30毫升(3毫克/千克体重)后,乳清中抑制原囊藻的值至少在6小时内明显。在一个季度内一次应用200毫升,在乳清中产生的抑制原囊藻的值在稀释至1:4时可持续36小时。给牛口服高剂量的丙硫咪唑,不会导致乳清中出现抑制原囊藻的值。

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