Bergmann A
Institut für Mikrobiologie und Tierseuchenlehre, Universität Leipzig.
Berl Munch Tierarztl Wochenschr. 1993 Aug;106(8):253-6.
Preparations with 4 percent Tetramisole or Levamisole hydrochloride were compatible in the mammary gland after application up to 40 ml/quarter (4 mg/kg body mass) for up to 6 milking times. 100 ml of the preparations were also clinically compatible in a single quarter (10 mg/kg body mass) on several days. After intramammary application of 30 ml/quarter (3 mg/kg body mass) Prototheca suppressing values in milk serum were evident for at least 6 hours. One application of 200 ml in one quarter has caused Prototheca suppressing values for 36 hours in milk serum up to dilution 1:4. Nilverm given to cattle in high dosage orally did not lead to Prototheca suppressing values in milk sera.
含4%盐酸四咪唑或盐酸左旋咪唑的制剂,在每季度应用多达40毫升(4毫克/千克体重)、最多挤奶6次后,在乳腺中是相容的。100毫升该制剂在单季度(10毫克/千克体重)连续数天应用时在临床上也是相容的。每季度乳腺内应用30毫升(3毫克/千克体重)后,乳清中抑制原囊藻的值至少在6小时内明显。在一个季度内一次应用200毫升,在乳清中产生的抑制原囊藻的值在稀释至1:4时可持续36小时。给牛口服高剂量的丙硫咪唑,不会导致乳清中出现抑制原囊藻的值。