[Properties of anti-LH-RH serums induced by 2 different immunogens].

Several anti-LH RH antisera have been raised in Rabbits given as immunogen the synthetic decapeptide linked to bovine serum albumin by carbodiimide or bis-diazotized benzidine. Antibodies obtained with CDI as a coupling agent showed the highest titers and affinities enabling measurement of LH RH levels lower than 1 pg/tube. The specificity of the antisera, particularly toward 13 fragments of the molecule, were similar irrespective of the immunogen used.