Koeppel M C, Sayag J
CHU Timone Adultes, Service de Dermatologie Vénérologie, Marseille.
Allerg Immunol (Paris). 1993 Sep;25(7):286-8.
Tryptase (T), chymase (C), carboxypeptidase A, cathepsin G-like constituent of preformed mediators contained in mastocyte granules, are a group of neutral proteases with proteolytic activity. These enzymes gives differentiation of two groups of mastocytes, MCTC and MCT as a function of the richness of enzymes. Although the functions of these molecules are becoming better and better understood, their exact roles as well as that of their inhibitors, still remain to be explored in urticaria.