针对疟疾和其他媒介传播疾病的传播阻断免疫。
Transmission-blocking immunity against malaria and other vector-borne diseases.
作者信息
Kaslow D C
机构信息
Laboratory of Malaria Research, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892.
出版信息
Curr Opin Immunol. 1993 Aug;5(4):557-65. doi: 10.1016/0952-7915(93)90037-s.
PMID:8216932
Abstract
Antibodies to sexual stage malaria parasites block transmission of Plasmodium by female mosquitoes. With the recent isolation of genes encoding several of the target antigens of transmission-blocking antibodies, the development of a subunit transmission-blocking vaccine against malaria is now a realistic goal.
摘要
针对有性期疟原虫的抗体可阻止雌性蚊子传播疟原虫。随着最近编码几种传播阻断抗体靶抗原的基因被分离出来，开发一种抗疟疾的亚单位传播阻断疫苗现在已成为一个现实的目标。
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