Nathan P, MacMillan B G
CRC Crit Rev Clin Lab Sci. 1976 May;7(1):1-31. doi: 10.3109/10408367609151685.
Skin allografts and xenografts are routinely used as dressings to control infection, pain and fluid loss from the burn wound. The procedure for preparing and storing grafts will be reviewed and suggested indications for use will be considered. A method for preparing porcine xenograft will be discussed in some detail. Skin banking by low temperature preservation including conditions and processing necessary for obtaining viable grafts will be discussed. The use of tissue typing matching procedures for obtaining prolonged survival will be considered. Possible harmful effects of grafts will be reviewed. The use of blood and blood products for resuscitation of burn patients is of primary importance in burn patients. The literature will be reviewed concerning a variety of blood and blood products including a consideration of washed cells, single donoplasma, serum albumin and purified blood components for treatment of burned patients. The use and indications for hyper-immune serum and gammu-globulin will be considered. Coagulopathy syndromes, burn wound sepsis, and support of immunologically deficient patients will be discussed on the basis of current literature.
皮肤同种异体移植和异种移植通常用作敷料，以控制烧伤创面的感染、疼痛和液体流失。将回顾制备和储存移植物的程序，并考虑建议的使用指征。将详细讨论一种制备猪异种移植物的方法。将讨论通过低温保存进行皮肤库储存，包括获得可行移植物所需的条件和处理过程。将考虑使用组织分型匹配程序以延长移植物存活时间。将回顾移植物可能的有害影响。在烧伤患者中，使用血液和血液制品进行复苏至关重要。将回顾有关各种血液和血液制品的文献，包括对洗涤细胞、单采血浆、血清白蛋白和纯化血液成分用于治疗烧伤患者的考虑。将考虑使用超免疫血清和γ-球蛋白的指征。将根据当前文献讨论凝血病综合征、烧伤创面脓毒症以及免疫缺陷患者的支持治疗。
