Nopkesorn T, Mastro T D, Sangkharomya S, Sweat M, Singharaj P, Limpakarnjanarat K, Gayle H D, Weniger B G
Somdej Pranaresuan Maharaj Hospital, Phitsanuloke, Bangkok, Thailand.
AIDS. 1993 Sep;7(9):1233-9. doi: 10.1097/00002030-199309000-00013.
To determine risk factors for HIV-1 infection in young men in northern Thailand.
At enrollment into a prospective study, data were collected from a self-administered questionnaire and serologic testing on a cohort of 1115 young men selected by lottery for conscription.
The overall HIV-1 infection rate was 6.9%; however, the rate was 15.3% among the 387 (34.7%) men who had been living in the upper north subregion of Thailand compared with 2.5% for the remaining 728 men (P < 0.001). A history of sex with female prostitutes was reported by 74.7% of men and increased frequency of this type of sex was highly associated with HIV-1 infection and a history of sexually transmitted disease (STD) symptoms (chi 2 for trend, P < 0.001). In stratified and multivariate analyses, however, history of STD symptoms, reported by 42.5% of the cohort, was most strongly associated with HIV-1 infection. Only 42.8% of men who reported sex with prostitutes had used condoms more than half the time.
Young men in the general population in northern Thailand are at high risk for HIV-1 infection via sex with female prostitutes; STD are highly associated with HIV-1 infection. Increasing condom use and controlling STD should be immediate goals of HIV control programs.
确定泰国北部年轻男性感染HIV-1的危险因素。
在一项前瞻性研究的入组阶段，通过自我填写问卷以及对1115名通过抽签选定的应征入伍年轻男性队列进行血清学检测来收集数据。
HIV-1总体感染率为6.9%；然而，在曾居住在泰国北部上地区域的387名男性（占34.7%）中，感染率为15.3%，而其余728名男性的感染率为2.5%（P<0.001）。74.7%的男性报告有与女性性工作者发生性行为的历史，这种性行为频率的增加与HIV-1感染以及性传播疾病（STD）症状史高度相关（趋势检验卡方值，P<0.001）。然而，在分层分析和多变量分析中，该队列中42.5%的男性报告有STD症状史，这与HIV-1感染的关联最为强烈。在报告与性工作者发生性行为的男性中，只有42.8%的人超过一半的时间使用了避孕套。
泰国北部普通人群中的年轻男性通过与女性性工作者发生性行为感染HIV-1的风险很高；STD与HIV-1感染高度相关。增加避孕套的使用和控制STD应成为HIV控制项目的近期目标。
