García-Ortega F P, Herrero F, Pretel L, Sánchez-Celemin F
Servicio de ORL, Hospital Universitario Arrixaca, Murcia.
Acta Otorrinolaringol Esp. 1993 Jul-Aug;44(4):309-10.
A 21-year-old man with 3-month history of hoarseness and dyspnea was suspected to have Wegener's granulomatosis with initially appearing in the trachea. In spite of unspecific biopsies, the clinicopathological picture and the high titles of anticytoplasmic autoantibodies (ACPA) confirmed the diagnosis. The early treatment with cyclophosphamide impeded the evolution to graver systemic forms of the disease.
一名21岁男性,有3个月声音嘶哑和呼吸困难病史,怀疑患有韦格纳肉芽肿,最初病变位于气管。尽管活检结果不具特异性,但临床病理表现和高滴度的抗细胞质自身抗体(ACPA)确诊了该疾病。早期使用环磷酰胺治疗阻止了疾病向更严重的全身性形式发展。