Gu R D
First Affiliated Hospital of Najing Medical College.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(2):100-1, 124-5.
It is well known that prostaglanding are biological mediators which are closely related to inflammation and immunity. To explore the role of PGE2 and PGF2 alpha in inflammation and immunity of human palatine tonsils, the levels of PGE2 and PGF2 alpha in diseased tonsils from 62 patients were measured. It is suggested that PGE2 and PGF2 alpha are present in the tonsillar tissue as inflammatory mediators. The levels of PGE2 and PGF2 alpha may be regarded as the major indicators of activation in chronic tonsillitis and represent the immunologic function of the palatine tonsils to a certain degree. The impairment of the ability of immunologic response in tonsils by inflammation may be related to PGE2. The more severe the inflammation, the more hazardous to the local immunologic defence of tonsils is. It is possible that PGE2 plays an important role in this respect.
众所周知，前列腺素是与炎症和免疫密切相关的生物介质。为了探究前列腺素E2（PGE2）和前列腺素F2α（PGF2α）在人腭扁桃体炎症和免疫中的作用，对62例患者患病扁桃体中PGE2和PGF2α的水平进行了测定。结果表明，PGE2和PGF2α作为炎症介质存在于扁桃体组织中。PGE2和PGF2α的水平可被视为慢性扁桃体炎激活的主要指标，并在一定程度上代表腭扁桃体的免疫功能。炎症对扁桃体免疫反应能力的损害可能与PGE2有关。炎症越严重，对扁桃体局部免疫防御的危害就越大。PGE2在这方面可能起重要作用。
