Tsipouras P, Devereux R B
Department of Pediatrics, University of Connecticut Health Center, Farmington 06030.
Semin Dermatol. 1993 Sep;12(3):219-28.
Marfan syndrome is a systemic heritable disorder of connective tissue. The manifestations of the disorder are primarily from the musculoskeletal, cardiovascular, and ocular systems. Marfan syndrome is caused by mutations in the fibrillin gene located on chromosome 15.
马凡综合征是一种全身性遗传性结缔组织疾病。该疾病的表现主要源于肌肉骨骼、心血管和眼部系统。马凡综合征由位于15号染色体上的原纤蛋白基因突变引起。
