长期喂食格列本脲对正常大鼠的影响。
Effects of long-term feeding of glibenclamide on normal rats.
作者信息
George A V, Augusti K T
出版信息
Experientia. 1976;32(7):846-7. doi: 10.1007/BF02003721.
PMID:821775
Abstract
Prolonged administration of glibenclamide decreased blood sugar, liver glycogen and protein and increased liver and serum lipids and organic phosphates of liver in normal rats. A significant weight increase observed in glibenclamide group of rats is attributed to lipid accumulation.
摘要
在正常大鼠中，长期给予格列本脲可降低血糖、肝糖原和蛋白质水平，并增加肝脏和血清脂质以及肝脏中的有机磷酸盐含量。格列本脲组大鼠体重显著增加归因于脂质蓄积。
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