Kassayová M, Ahlersová E, Ahlers I
Institute of Animal Physiology, Faculty of Science, Safárik University, Kosice, Slovak Republic.
Physiol Res. 1993;42(3):167-9.
Male Wistar rats were exposed to whole body irradiation with 14.35 Gy gamma rays after the adaptation to light/dark cycle (LD 12:12). Three groups of rats were examined: A) rats irradiated in the night and placed in the 12 h LD cycle again, B) rats irradiated in the day-time and placed in the 12 h LD cycle, and C) rats irradiated in the night and kept in constant darkness. All analyses were carried out in the dark. Radiation enhanced the activity of pineal N-acetyltransferase 3-4 days after exposure in all groups, in the C group significantly on the 4th day. Different light regimens during and after irradiation did not to affect the activity of this key enzyme of melatonin synthesis substantially.
雄性Wistar大鼠在适应光/暗周期（LD 12:12）后接受14.35 Gyγ射线全身照射。检查了三组大鼠：A）夜间照射的大鼠并再次置于12小时光/暗周期中，B）白天照射的大鼠并置于12小时光/暗周期中，以及C）夜间照射的大鼠并置于持续黑暗中。所有分析均在黑暗中进行。照射后3-4天，辐射增强了所有组松果体N-乙酰转移酶的活性，C组在第4天显著增强。照射期间和照射后的不同光照方案基本上不影响褪黑素合成关键酶的活性。
