Straus D J
Memorial Sloan-Kettering Cancer Center, New York, New York.
Curr Opin Oncol. 1993 Sep;5(5):785-90. doi: 10.1097/00001622-199309000-00003.
Recent studies are refining the treatment approaches of radiation therapy and combination chemotherapy in Hodgkin's disease. In early-stage disease, attempts are being made to lessen the toxicity of treatment while maintaining excellent results. Optimal results are achieved in advanced disease with combined radiation therapy and chemotherapy, most often with alternating or hybrid regimens. Several groups have attempted to define a poor-prognosis group of patients with advanced disease who might be candidates for more intensive treatment.
近期的研究正在完善霍奇金淋巴瘤的放射治疗和联合化疗的治疗方法。对于早期疾病,人们正在努力在保持良好疗效的同时降低治疗的毒性。对于晚期疾病,联合放射治疗和化疗可取得最佳效果,最常用的是交替或混合方案。有几个研究小组试图确定一组晚期疾病预后较差的患者,这些患者可能是更强化治疗的候选对象。