Schick F, Duda S, Laniado M, Jung W I, Claussen C D, Lutz O
Abteilung für Radiologische Diagnostik, Eberhard-Karls-Universität Tübingen.
Rofo. 1993 Oct;159(4):325-30. doi: 10.1055/s-2008-1032773.
The method of localised 1H MR spectroscopy was used in 19 examinations in 9 patients with primary bone tumours in order to obtain spectral signals and to determine whether these are specific for tumour classification. The spectra were obtained by a double spin echo method and the tumour tissue showed very high water content and only minor lipid and proton signals which showed J-coupling characteristics. The latter are not found in normal bone marrow and are probably due to products of tumour metabolism. The resolution of the spectra within a 13 mm or 20 mm tissue cube depends largely on the structural homogeneity of the tumour. The signal patterns in the spectra were not specific to histological tumour types.
对9例原发性骨肿瘤患者进行了19次局部1H磁共振波谱检查，以获取光谱信号并确定这些信号是否对肿瘤分类具有特异性。通过双自旋回波方法获得光谱，肿瘤组织显示出非常高的含水量，只有少量脂质和质子信号，这些信号显示出J耦合特征。后者在正常骨髓中未发现，可能是肿瘤代谢产物所致。在13毫米或20毫米组织块内的光谱分辨率很大程度上取决于肿瘤的结构均匀性。光谱中的信号模式对组织学肿瘤类型不具有特异性。
