Tikkakoski T, Lohela P, Taavitsainen M, Hiltunen S, Ihalainen J, Päivänsalo M, Siniluoto T, Strengel L, Apaja-Sarkkinen M
Department of Diagnostic Radiology, Keski-Pohjanmaa Central Hospital, Kokkola, Finland.
Rofo. 1993 Nov;159(5):444-9. doi: 10.1055/s-2008-1032795.
We reviewed the results of US-guided fine-needle biopsies of peripheral pulmonary, pleural, mediastinal and chest wall lesions in 200 patients. Sufficient material for cytological analysis was obtained in 95%, 92%, 96% and 100%, respectively. Sensitivity was 88%, 94%, 96%, 100% and specificity 89%, 100% and 100%, respectively. The ratio of false-negative results was 7%. A cutting needle biopsy was additionally performed in 24 patients. All but two of the histological samples (92%) were adequate for diagnostic purposes and a correct diagnosis was established in 86% (19/22) of these. 8 patients (4%) with pleural or pulmonary targets had minor complications (5 pneumothorax, 3 haemoptysis), which did not require treatment. Cutting needle biopsies and biopsy of mediastinal lesions proved safe. Due to the many advantages US may be considered for guidance in peripheral larger-sized pulmonary lesions, particularly those abutting the pleura, and also in pleural, thoracic wall and mediastinal masses.
我们回顾了200例患者经超声引导对周围肺部、胸膜、纵隔及胸壁病变进行细针穿刺活检的结果。分别有95%、92%、96%和100%的患者获得了足够用于细胞学分析的材料。敏感性分别为88%、94%、96%、100%,特异性分别为89%、100%和100%。假阴性结果的比例为7%。另外对24例患者进行了切割针活检。除两例外,所有组织学样本(92%)均足以用于诊断目的,其中86%(19/22)的样本确立了正确诊断。8例(4%)胸膜或肺部目标病变患者出现轻微并发症(5例气胸,3例咯血),无需治疗。切割针活检及纵隔病变活检被证明是安全的。由于具有诸多优点,超声可用于引导对周围较大的肺部病变进行活检,尤其是那些靠近胸膜的病变,也可用于引导对胸膜、胸壁及纵隔肿物进行活检。