Schimkat M, Horstkotte D, Sundmacher R
Universitäts-Augenklinik Düsseldorf.
Ophthalmologe. 1993 Oct;90(5):476-8.
Retinal vessel occlusion in the elderly is considered to be of arteriosclerotic etiology, but in young patients the reasons for retinal vessel occlusions are manifold and much more obscure. We report on five patients under the age of 45 years who had retinal artery occlusion or retinal vein obstruction. A detailed general investigation revealed nothing but an identical cardiac abnormality in all five cases: mitral valve prolapse (MVP). A potential explanation for the coincidence of retinal vessel occlusion and MVP might be local hyperaggregability of platelets generated by the prolapsing mitral valve. In conclusion, to prevent retinal vessel occlusion from recurring in patients with proven MVP, medication containing platelet aggregation inhibitors should be given.
老年人视网膜血管阻塞被认为是动脉硬化病因,但在年轻患者中,视网膜血管阻塞的原因多种多样且更为隐匿。我们报告了5例45岁以下患有视网膜动脉阻塞或视网膜静脉阻塞的患者。详细的全身检查除了发现所有5例患者都有相同的心脏异常:二尖瓣脱垂(MVP)外,没有其他发现。视网膜血管阻塞与MVP同时出现的一个可能解释可能是脱垂的二尖瓣产生的血小板局部高聚集性。总之,为防止确诊为MVP的患者视网膜血管阻塞复发,应给予含血小板聚集抑制剂的药物。