Bluschke V, Hennerici M, Scharf R E, Kladetzky R G, Breithardt G, Lück J, Köhler E
Dtsch Med Wochenschr. 1982 Mar 19;107(11):410-4. doi: 10.1055/s-2008-1069945.
In 47 patients under 45 years of age (average age 35.4 years) with more or less localised cerebral ischaemia without evidence of arteriosclerosis echocardiography showed mitral valve prolapse in 13 cases. This was slightly more frequent than in an age and sex-matched control group. The difference was not statistically significant. In three quarters of the patients (n = 35) a significantly raised beta-thromboglobulin level was found indicating increased platelet activity. No definite conclusions can be drawn as to the cause of cerebral ischaemia which is probably due to embolism. However, treatment with platelet aggregation inhibitors should be considered.
在47例45岁以下（平均年龄35.4岁）有局限性脑缺血且无动脉硬化证据的患者中，超声心动图显示13例有二尖瓣脱垂。这比年龄和性别匹配的对照组略为常见。差异无统计学意义。四分之三的患者（n = 35）β-血小板球蛋白水平显著升高，表明血小板活性增加。关于可能由栓塞引起的脑缺血原因无法得出明确结论。然而，应考虑使用血小板聚集抑制剂进行治疗。
