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[免疫闪烁显像在脉络膜恶性黑色素瘤中的敏感性]

[Sensitivity of immunoscintigraphy in malignant melanoma of the choroid].

作者信息

Stanowsky A, Krey H F, Kanitz W, Kopp J, Wagner T

机构信息

Augenklinik, Zentralklinikum Augsburg.

出版信息

Ophthalmologe. 1993 Oct;90(5):501-5.

PMID:8219640
Abstract

Between June, 1988 and May, 1991 30 patients with clinically suspected malignant melanoma were examined in succession by means of immunoscintigraphy and the 225.28 S antibody (tagged with Tc-99m). Retrospectively, the results showed a sensitivity of over 70% by SPECT examination. Positive accumulation of the antibody within the suspected melanoma gives reason to believe that this degree of accuracy can be improved by comparative application of unspecific, radioactively tagged proteins. In the absence of accumulation within clinically, and in particular echographically, confirmed malignant melanoma treatment should be performed.

摘要

在1988年6月至1991年5月期间,连续对30例临床疑似恶性黑色素瘤患者进行了免疫闪烁扫描检查,并使用了225.28 S抗体(用锝-99m标记)。回顾性分析结果显示,单光子发射计算机断层扫描(SPECT)检查的敏感性超过70%。疑似黑色素瘤内抗体的阳性聚集表明,通过比较应用非特异性放射性标记蛋白,有望提高这种检查的准确性。如果在临床,尤其是超声检查确诊的恶性黑色素瘤内未发现抗体聚集,则应进行治疗。

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