Samoĭlov A V, Seĭfulla R D, Kamaev N O, Tunitskaia T A, Teplova N P, Karmanovskiĭ A Ia, Belous M V
Eksp Klin Farmakol. 1993 May-Jun;56(3):37-9.
The paper outlines a new mode of intravascular anabolic steroidal transport. The single intravenous administration of metandrostenolone aqueous solution to rats increases hypertrophy rate of MM. plantaris. It was shown that the action of a single dose (0.05 mg/kg) exceeded that of metandrostenolone oil solution in a dose of 5 mg/kg. The multiple reduction of doses of the anabolic drug and the high level of bioavailability were achieved. This effect was explained by the application of the specific transport agent.
本文概述了一种新的血管内合成代谢甾体转运模式。对大鼠单次静脉注射美雄酮水溶液可提高趾长伸肌的肥大率。结果表明，单次剂量（0.05mg/kg）的作用超过了5mg/kg剂量的美雄酮油溶液。实现了合成代谢药物剂量的多次减少和高生物利用度。这种效应是通过应用特定的转运剂来解释的。
