Camera A, Piccirillo G, Cennamo G, Tranfa F, Rosa N, Frigeri F, Martinelli V, Rotoli B
Divisione di Ematologia, Facoltà di Medicina, Università Federico II, Napoli, Italy.
Leuk Lymphoma. 1993 Sep;11(1-2):153-5. doi: 10.3109/10428199309054745.
Leukemic infiltration of the optic nerve is rare. We describe the diagnostic assessment and the outcome in two adult patients suffering from acute lymphoblastic leukemia with T phenotype. In both cases the leukemic involvement of the eye was observed as an isolated extramedullary relapse followed after several months by hematological relapse. CT and MRI scans were negative, while an A-scan echography of the eye clarified the diagnosis. Early radiotherapy caused recovery of visual acuity in one case. A-scan echography is the most sensitive investigation for the early recognition of ocular localization in acute leukemias.
视神经的白血病浸润较为罕见。我们描述了两名患有T表型急性淋巴细胞白血病的成年患者的诊断评估及结果。在这两例病例中，眼部的白血病累及均表现为孤立的髓外复发，数月后出现血液学复发。CT和MRI扫描结果均为阴性，而眼部A超检查明确了诊断。早期放疗使其中一例患者的视力得以恢复。A超检查是早期识别急性白血病眼部定位最敏感的检查方法。
