Fogelholm G M, Näveri H K, Kiilavuori K T, Härkönen M H
Dept. of Applied Chemistry and Microbiology, University of Helsinki, Finland.
Int J Sport Nutr. 1993 Sep;3(3):290-7. doi: 10.1123/ijsn.3.3.290.
Using a double-blind, crossover protocol, we studied the possible effects of a 4-day combined L-arginine, L-ornithine, and L-lysine supplementation (each 2 g/day, divided into two daily doses) on 24-hr level of serum human growth hormone (hGH) and insulin in 11 competitive weightlifters, ages 19 to 35 yrs. Three similar daily hGH peaks, seemingly preceded by a decrease in serum insulin concentration, were found during both amino acid and placebo supplementation. Supplementation did not affect the physiological variation of serum hGH concentration (treatment and treatment x time interaction: p = 0.43-0.55). Analogously, serum insulin levels were not higher after amino acid supplementation. Therefore the ergogenic value of low-dose oral amino acid supplementation in increasing hGH or insulin secretion seems questionable.
我们采用双盲交叉试验方案，研究了连续4天补充L-精氨酸、L-鸟氨酸和L-赖氨酸（各2克/天，分两次服用）对11名年龄在19至35岁的竞技举重运动员血清人生长激素（hGH）和胰岛素24小时水平的可能影响。在补充氨基酸和安慰剂期间，均发现了三个相似的每日hGH峰值，且似乎在血清胰岛素浓度下降之前出现。补充并未影响血清hGH浓度的生理变化（治疗及治疗×时间交互作用：p = 0.43 - 0.55）。类似地，补充氨基酸后血清胰岛素水平也未升高。因此，低剂量口服补充氨基酸在增加hGH或胰岛素分泌方面的促力值似乎存疑。
