Tyshko A G, Bebko Iu M
Mikrobiol Z. 1993 Jun-Aug;55(4):64-8.
Under local experimental infection induced by bacteroides of Fragilis group the factors of nonspecific organism resistance take an active part in the inflammation process. Phase changes of the state of monocytic-phagocytic and complement systems were observed. Peripheral blood leukocyte phagocytic activity decreased at the primary stage, then followed the complement activation by the alternative pathway mainly. The increase of phagocytic and metabolic activities of those phagocytes taking part in the inflammation, the complement at this stage is activated due to the classical pathway while being at the stage of clinic manifestation. Levels of antibody titres are also increasing.
在脆弱拟杆菌属局部实验性感染诱导下,机体非特异性抵抗因子积极参与炎症过程。观察到单核吞噬细胞系统和补体系统状态的阶段性变化。外周血白细胞吞噬活性在初期降低,随后主要通过替代途径激活补体。参与炎症的吞噬细胞的吞噬和代谢活性增加,在临床表现阶段,补体通过经典途径被激活。抗体滴度水平也在升高。