Cuche J L, Ott C E, Marchand G R, Knox F G
J Lab Clin Med. 1976 Aug;88(2):271-5.
A possible effect of decreased plasma ionized calcium concentration on renal phosphate handling was investigated in dogs with control of parathyroid hormone. Intrarenal artery infusion of either EDTA or sodium citrate decreased ionized calcium concentration 25 per cent in renal vein blood but had no significant effect on fractional phosphate excretion. Similarly, intravenous infusion of chelators had no significant effect on fractional phosphate excretion. It is concluded that acute decreases in ionized calcium have no significant effect on the renal handling of phosphate.
在甲状旁腺激素得到控制的犬类中，研究了血浆离子钙浓度降低对肾脏磷酸盐处理的可能影响。肾内动脉输注乙二胺四乙酸（EDTA）或柠檬酸钠可使肾静脉血中离子钙浓度降低25%，但对磷酸盐排泄分数无显著影响。同样，静脉输注螯合剂对磷酸盐排泄分数也无显著影响。得出的结论是，离子钙的急性降低对肾脏处理磷酸盐没有显著影响。
