Ferrando R, Truhaut R
Bull Acad Natl Med. 1993 May;177(5):775-83; discussion 783-7.
The pathogenicity of aflatoxins for human has been largely demonstrated. Although aflatoxin contamination of some foodstuffs has been unquestionably established, stress should be laid upon a certain lack of information: some of the affected foodstuffs have been "forgotten" in the enumeration of contaminated products (especially soybeans); relations between mycotoxins and food balance have not yet been taken into account: for instance, the influence of some vitamins, of various compounds (carotenoids, methionine, ...), influence of deficiency in proteins (often very important in Africa) etc... aflatoxin bioavailability has not sufficiently been examined (particularly that of milk aflatoxin M1.); concerning aflatoxin evaluation in contaminated products, it should be known that their distribution is very irregular. Sampling and following analysis should thus be carried out most carefully; for these motives, some conditions and likewise regulations would can again scrutinized.
黄曲霉毒素对人类的致病性已得到充分证明。虽然某些食品中黄曲霉毒素的污染已确凿无疑，但应强调信息仍存在一定不足：在受污染产品（尤其是大豆）的列举中，一些受影响的食品被“遗漏”了；霉菌毒素与食物平衡之间的关系尚未得到考虑：例如，某些维生素、各种化合物（类胡萝卜素、蛋氨酸等）的影响，蛋白质缺乏（在非洲往往非常严重）的影响等……黄曲霉毒素的生物可利用性尚未得到充分研究（尤其是牛奶中黄曲霉毒素M1的生物可利用性）；关于受污染产品中黄曲霉毒素的评估，应该知道它们的分布非常不均匀。因此，采样和后续分析应极其谨慎地进行；出于这些原因，一些条件以及相关规定可能需要再次审视。
