重症肌无力的电诊断研究

Electrodiagnostic studies in myasthenia gravis.

作者信息

Lyu R K, Cheng S Y, Tang L M

机构信息

Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.

出版信息

Changgeng Yi Xue Za Zhi. 1993 Sep;16(3):164-9.

PMID:8221289

Abstract

Forty-three patients with myasthenia gravis (MG) were studied to compare the sensitivity of repetitive nerve stimulation (RNS) test with single fiber electromyography (SFEMG) in the diagnosis of MG. SFEMG was abnormal in 81% (35 of 43 cases), while RNS test was abnormal in 53% (23 of 43 cases). In ocular MG, SFEMG showed a much higher positive rate (70%, 16 of 23 cases) than RNS test (22%, 5 of 23 cases). Both studies had similar abnormal rates in the generalized group. In patients studied with SFEMG in the EDC muscle, the clinical severity was closely correlated with jitter abnormality. We conclude that SFEMG is more sensitive than RNS test in the diagnosis of MG, especially in the ocular group.

摘要

对43例重症肌无力（MG）患者进行研究，以比较重复神经电刺激（RNS）试验与单纤维肌电图（SFEMG）在MG诊断中的敏感性。SFEMG异常率为81%（43例中的35例），而RNS试验异常率为53%（43例中的23例）。在眼肌型MG中，SFEMG的阳性率（70%，23例中的16例）远高于RNS试验（22%，23例中的5例）。在全身型组中，两项研究的异常率相似。在用SFEMG研究的指总伸肌（EDC）肌肉患者中，临床严重程度与颤抖异常密切相关。我们得出结论，在MG诊断中，尤其是在眼肌型组中，SFEMG比RNS试验更敏感。