Coustan D R
Department of Obstetrics and Gynecology, Brown University School of Medicine, Providence, Rhode Island.
Clin Perinatol. 1993 Sep;20(3):593-602.
Screening for gestational diabetes should be performed using a 50-g 1-hour glucose challenge. The threshold for further testing may be chosen based on the goal of the screening program, either to maximize sensitivity at the expense of more diagnostic testing by using a 130 mg/dL cutoff or to increase specificity at the sacrifice of some sensitivity by using a 140 mg/dL cutoff. The choice of universal screening or an age cutoff, such as 25 years, with testing reserved in younger women for those with risk factors, is dependent on the characteristics of a given patient population or practice. The diagnostic test for gestational diabetes is the 100-g 3-hour oral glucose tolerance test on venous plasma or serum specimens. Whole blood values may be used, but the use of capillary blood measurements by test strips and reflectance meters is not recommended.
妊娠期糖尿病的筛查应采用50克1小时葡萄糖耐量试验。进一步检测的阈值可根据筛查项目的目标来选择，要么以更多诊断检测为代价，通过采用130毫克/分升的临界值来最大化敏感性，要么以牺牲一些敏感性为代价，通过采用140毫克/分升的临界值来提高特异性。选择普遍筛查还是年龄临界值（如25岁），对年轻女性中具有危险因素的人群进行检测，取决于特定患者群体或医疗机构的特点。妊娠期糖尿病的诊断试验是对静脉血浆或血清标本进行100克3小时口服葡萄糖耐量试验。可以使用全血值，但不建议使用试纸条和反射仪进行毛细血管血测量。
