Kinasewitz G T
Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City.
Clin Chest Med. 1993 Sep;14(3):523-36.
The incidence of deep venous thrombosis and subsequent pulmonary embolism is increased in the elderly but, because the clinical manifestations may be misleading, the diagnosis is often missed. The clinician must maintain a high index of suspicion and order specific tests for venous thrombosis or pulmonary embolism whenever these diagnoses are considered. Even though the risk of bleeding while anticoagulated is increased in the elderly, treatment with heparin followed by long-term anticoagulation with warfarin is the preferred course of therapy for most patients. Awareness of their increased risk and emphasis on prevention of venous thrombosis may be the most effective means of dealing with this clinical problem in the elderly.
老年人深静脉血栓形成及随后发生肺栓塞的发生率增加,但由于临床表现可能具有误导性,诊断常常被漏诊。临床医生必须保持高度的怀疑指数,每当考虑这些诊断时,应安排针对静脉血栓形成或肺栓塞的特异性检查。尽管老年人抗凝治疗时出血风险增加,但对大多数患者而言,首选的治疗方案是先使用肝素治疗,随后长期使用华法林抗凝。认识到他们增加的风险并强调预防静脉血栓形成,可能是应对老年人这一临床问题的最有效手段。