Hypomelanosis of Ito and precocious puberty.
作者信息
Daubeney P E, Pal K, Stanhope R
机构信息
Hospitals for Sick Children, London, United Kingdom.
出版信息
Eur J Pediatr. 1993 Sep;152(9):715-6. doi: 10.1007/BF01953982.
PMID:8223798
Abstract
We describe two girls with hypomelanosis of Ito, one of whom was demonstrated to have diploid-triploid mixoploidy in skin fibroblasts. Both had precocious puberty which was probably gonadotrophin-independent. The association of precocious puberty and hypomelanosis of Ito has not been previously reported. We have speculated on the possible mechanism of gonadotrophin-independent precocious puberty.
摘要
Zotero 插件