Gado M H, Phelps M E, Hoffman E J, Raichle M E
Radiology. 1976 Oct;121(1):105-9. doi: 10.1148/121.1.105.
The relationship of the mean transit time of the vascular indicator C15O-labeled hemoglobin (tco) and the cerebral blood volume (CBV) as measured by stimulated x-ray fluorescence, to the mean arterial blood pressure (MABP) was examined in rhesus monkeys before and during experiment cerebral seizures. The results demonstrate a marked increase in CBV and a decrease in tco. A substantial portion of these changes is the passive accompaniment of the associated increase in MABP.
在恒河猴实验性癫痫发作前和发作期间，研究了血管指示剂C15O标记血红蛋白的平均通过时间（tco）以及通过激发X射线荧光测量的脑血容量（CBV）与平均动脉血压（MABP）之间的关系。结果表明，CBV显著增加，tco降低。这些变化的很大一部分是MABP相关增加的被动伴随现象。
