Loke D F, Viegas O A, Ratnam S S
Department of Obstetrics and Gynecology, National University of Singapore, National University Hospital.
Gynecol Obstet Invest. 1993;36(2):108-13. doi: 10.1159/000292606.
Serum lipid profiles were studied in 167 healthy fertile Singaporean women, aged between 18 and 40 and comprising 114 Chinese, 28 Malays and 25 Indians. Parity or ethnic differences did not affect lipid concentrations. Except for triglycerides which showed a decreasing trend, there was no significant variation in lipid concentrations with age. However, all lipid concentrations except HDL cholesterol (which decreased) appeared to increase with body mass index. Compared with other populations, these Singaporean women appeared to have higher mean concentrations of total cholesterol and lower mean concentrations of HDL cholesterol. The possibility that these differences could have contributed to the increasing incidence of coronary heart disease in Singapore is discussed.
对167名年龄在18至40岁之间的健康可育新加坡女性进行了血脂谱研究,其中包括114名华人、28名马来人和25名印度人。生育状况或种族差异不影响血脂浓度。除甘油三酯呈下降趋势外,血脂浓度随年龄无显著变化。然而,除高密度脂蛋白胆固醇(HDL胆固醇,呈下降趋势)外,所有血脂浓度似乎都随体重指数增加。与其他人群相比,这些新加坡女性的总胆固醇平均浓度似乎较高,而高密度脂蛋白胆固醇平均浓度较低。文中讨论了这些差异可能导致新加坡冠心病发病率上升的可能性。