Bégin L R, Black M J
Department of Pathology, McGill University, Montreal, Québec, Canada.
Histopathology. 1993 Sep;23(3):283-5. doi: 10.1111/j.1365-2559.1993.tb01204.x.
A 38-year-old woman presented with otalgia and facial pain. She was found to have a tumour involving the right maxillary sinus and pterygopalatine fossa. Exclusively composed of a myxoid population of spindle and stellate cells within a mucosubstance-rich matrix, it was originally interpreted as a mesenchymal neoplasm. However, immunophenotypic characterization revealed a pure population of salivary-type myoepithelial cells with cytoplasmic co-expression of cytokeratin, vimentin, muscle-specific actin, S-100 protein and glial fibrillary acidic protein. Sinonasal myxoid myoepithelial neoplasia is exceedingly rare and represents a potential diagnostic pitfall.
一名38岁女性因耳痛和面部疼痛就诊。她被发现患有累及右上颌窦和翼腭窝的肿瘤。该肿瘤仅由富含黏液物质的基质中的梭形和星状细胞黏液样群体组成,最初被解释为间叶性肿瘤。然而,免疫表型特征显示为纯唾液腺型肌上皮细胞群体,细胞角蛋白、波形蛋白、肌肉特异性肌动蛋白、S-100蛋白和胶质纤维酸性蛋白在细胞质中共表达。鼻窦黏液样肌上皮瘤极为罕见,是一个潜在的诊断陷阱。