内皮素-1和冈田酸诱导羔羊气管平滑肌收缩。
Endothelin-1 and okadaic acid induced contractions in tracheal smooth muscle of lamb.
作者信息
Katoch S S
机构信息
II Physiology Institute, University of Heidelberg, Germany.
出版信息
Indian J Exp Biol. 1993 Jul;31(7):647-9.
PMID:8225422
Abstract
Stimulation of lamb tracheal smooth muscle fibre strips with endothelin-1 and okadaic acid results in the development of isometric tensions which are long lasting. However, endothelin-1 is more potent constrictor than okadaic acid. An analysis of 20,000 Da regulatory myosin light chain by two-dimensional gel electrophoresis shows an identical phosphorylation pattern.
摘要
用内皮素 -1 和冈田酸刺激羔羊气管平滑肌纤维条会导致产生持久的等长张力。然而，内皮素 -1 是比冈田酸更强效的收缩剂。通过二维凝胶电泳对 20,000 Da 调节性肌球蛋白轻链的分析显示出相同的磷酸化模式。
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