Haustein K O
Institute of Clinical Pharmacology, Medizinische Hochschule Erfurt, Germany.
Int J Clin Pharmacol Ther Toxicol. 1993 Aug;31(8):399-403.
In the present study, the consumption of several drugs on the territories of the former GDR and FRG was compared using 200,000 prescriptions and the defined daily doses (DDD). Furthermore, for the two parts of Germany, the 20 most frequently prescribed drugs were evaluated. Calcium antagonists and the beta-blockers prevailed in East Germany, while cardiac glycosides, vasodilators, reserpin-containing antihypertensives, bronchodilators (beta-adrenoceptor agonists), neuroleptics, tricyclic antidepressants, antacids, H2-receptor blockers, chondroprotectives were used 1.5 to 5 times more frequently in West Germany. Because in East Germany, a shortage of drugs was no longer observed in 1991, several other reasons for the "over-prescription" of drugs for the patients in West Germany must be mentioned.
在本研究中,利用20万份处方和限定日剂量(DDD)对前东德和西德地区几种药物的消费量进行了比较。此外,对德国的这两个地区最常处方的20种药物进行了评估。钙拮抗剂和β受体阻滞剂在东德占主导地位,而强心苷、血管扩张剂、含利血平的抗高血压药、支气管扩张剂(β肾上腺素受体激动剂)、抗精神病药、三环类抗抑郁药、抗酸剂、H2受体阻滞剂、软骨保护剂在西德的使用频率是东德的1.5至5倍。由于在1991年东德不再存在药品短缺的情况,所以必须提及西德患者药物“过度处方”的其他几个原因。