Lough D S, Kahl S, Solomon M B, Rumsey T S
Meat Science Research Laboratory, USDA, Beltsville, MD 20705-2350.
J Anim Sci. 1993 Oct;71(10):2659-65. doi: 10.2527/1993.71102659x.
The purpose of the study was to determine the effect of trenbolone acetate (TBA) on performance, plasma lipid metabolites, and carcass characteristics of growing ram and ewe lambs in two separate experiments. Treatments consisted of 1) a control, no implants, and 2) a TBA implant (60 mg of Finaplix; Hoechst-Roussel Agri-Vet). Twelve Rambouillet cross ram lambs (average 19.9 kg BW; Exp. 1) and 18 Suffolk-Hampshire ewe lambs (average 37.2 kg BW; Exp. 2) were given ad libitum access to a 77% forage/23% concentrate diet (15.5% CP and 2.14 Mcal of ME/kg). On d 0, six rams and nine ewes received TBA as an ear implant and six rams and nine ewes were designated as controls. Blood samples were collected via jugular venipuncture on d 0, 28, 56, and 84 and plasma was separated and analyzed for lipid metabolites. Rams (30.5 kg BW) and ewes (50.0 kg BW) were slaughtered after 93 and 91 d, respectively. Average daily gain was not affected by TBA in rams (117 g/d) or ewes (159 g/d). Nutrient intake restricted normal BW gains in the rams. Plasma concentrations of total cholesterol, high-density lipoprotein cholesterol, triglycerides, and nonesterified fatty acids were not affected by TBA in either rams or ewes. Trenbolone acetate had no effect on subcutaneous fat measurements in either rams or ewes. Lamb chops from rams implanted with TBA were less (P < .04) tender (5.58 vs 4.26 kg/1.27-cm core) than lamb chops from control rams. Additional studies examining growth and carcass composition are needed in ruminants implanted with anabolic steroids and fed high-forage diets.
本研究的目的是在两项独立实验中，确定醋酸群勃龙（TBA）对生长阶段公绵羊和母绵羊的生产性能、血浆脂质代谢产物以及胴体特性的影响。处理方式包括：1）对照组，不植入；2）植入TBA（60毫克的法尼普利；赫斯特-罗素农业兽医公司）。12只兰布耶杂交公绵羊（平均体重19.9千克；实验1）和18只萨福克-汉普郡母绵羊（平均体重37.2千克；实验2）可随意采食含77%粗饲料/23%精饲料的日粮（15.5%粗蛋白和2.14兆卡代谢能/千克）。在第0天，6只公绵羊和9只母绵羊通过耳部植入TBA，另外6只公绵羊和9只母绵羊作为对照。在第0、28、56和84天通过颈静脉穿刺采集血样，分离血浆并分析脂质代谢产物。公绵羊（体重30.5千克）和母绵羊（体重50.0千克）分别在93天和91天后屠宰。TBA对公绵羊（117克/天）或母绵羊（159克/天）的平均日增重没有影响。营养摄入限制了公绵羊的正常体重增加。公绵羊和母绵羊的血浆总胆固醇、高密度脂蛋白胆固醇、甘油三酯和非酯化脂肪酸浓度均不受TBA影响。醋酸群勃龙对公绵羊和母绵羊的皮下脂肪测量均无影响。植入TBA的公绵羊的羊排（5.58对4.26千克/1.27厘米核心）比对照公绵羊的羊排嫩度更低（P < .04）。需要对植入合成代谢类固醇并采食高粗饲料日粮的反刍动物进行更多关于生长和胴体组成的研究。
