Levine P H
Blood Research Laboratory, Medical Center of Central Massachusetts, Worcester 01605-2982.
J Clin Apher. 1993;8(2):120-5. doi: 10.1002/jca.2920080212.
This report reviews the natural history of hemophilia and the development of concentrates as the preferred form of treatment and discusses the nature of immune defect in persons with hemophilia. It examines the risk of hepatitis and effect of HIV infection on treatment protocols, and it surveys the status of the safety of modern concentrates and what we have to look forward to in the future.
本报告回顾了血友病的自然史以及作为首选治疗形式的浓缩物的发展,并讨论了血友病患者免疫缺陷的性质。它研究了肝炎风险以及HIV感染对治疗方案的影响,还调查了现代浓缩物的安全性状况以及我们对未来的展望。