Baum M
Division of Pediatric Nephrology, University of Texas Southwestern Medical Center, Dallas.
Hosp Pract (Off Ed). 1993 Nov 15;28(11):137-42, 147-8. doi: 10.1080/21548331.1993.11442879.
In this syndrome, all solutes are prevented from crossing the apical membrane of the proximal renal tubule cell; hence, investigations have focused on generalized transport dysfunction, namely intracellular ATP activity. Experiments suggest that intracellular adenine nucleotide degradation secondary to phosphate depletion causes a decline in ATP.
在这种综合征中，所有溶质都无法穿过近端肾小管细胞的顶端膜；因此，研究集中在全身性转运功能障碍，即细胞内ATP活性。实验表明，继发于磷酸盐耗竭的细胞内腺嘌呤核苷酸降解会导致ATP水平下降。
