免疫调节：从麻风病中汲取经验。
Immune regulation: learning from leprosy.
作者信息
Modlin R L, Bloom B R
机构信息
Division of Dermatology, University of California, Los Angeles, School of Medicine.
出版信息
Hosp Pract (Off Ed). 1993 Nov 15;28(11):71-4, 77-80, 83-4. doi: 10.1080/21548331.1993.11442874.
Abstract
The specific anergy seen in severe, disseminated leprosy appears to represent multifaceted actions of macrophages and suppressor T lymphocytes. Identification of cytokine mediation in these events helps to account for the immune system's "choice" of cellular versus humoral defenses--and points toward manipulation of cytokine switches for immunotherapy against infectious and autoimmune disease.
摘要
在严重的播散性麻风病中所见的特异性无反应性似乎代表了巨噬细胞和抑制性T淋巴细胞的多方面作用。确定这些事件中的细胞因子介导作用有助于解释免疫系统在细胞免疫与体液免疫防御方面的“选择”，并为针对感染性疾病和自身免疫性疾病的免疫治疗中操纵细胞因子开关指明了方向。
Zotero 插件