Kyrkanides S, Kjaer I, Fischer-Hansen B
Department of Orthodontics, School of Dentistry, University of Copenhagen, Denmark.
J Craniofac Genet Dev Biol. 1993 Jul-Sep;13(3):184-92.
The present study aims to investigate the normal maturity and growth of the basilar part of the occipital bone evaluated radiographically and histochemically during the first half of prenatal life. The material consisted of cranial bases from 49 normal human fetuses and, in addition, three separate occipital bones deviscerated from normal fetuses. The normal development of the basilar part of the occipital bone was divided into five maturity stages (OB-I to OB-V). Microscopic investigation confirmed the macroscopic findings described. For each stage the ventro-dorsal dimension of the occipital bone component was measured (LEN). The stages of (OB-I to OB-V) were related to gestational age (AGE), crown-rump length (CRL), LEN, and to the length of the humeral bone (HL). Close accordance was registered between OB stages and length values of the basilar part of the occipital bone, LEN, and length of the humeral bone, HL. A highly significant positive correlation was found between LEN and the parameters AGE, CRL, and HL values (P < 0.001). Standards for normal development of the basilar part of the occipital bone are considered important for evaluation of the pathological prenatal development of the cranial base.
本研究旨在通过影像学和组织化学方法，对产前生命前半期枕骨基底部的正常成熟和生长情况进行研究。材料包括49例正常人类胎儿的颅底，此外，还有从正常胎儿身上分离出的三块单独的枕骨。枕骨基底部的正常发育分为五个成熟阶段（OB-I至OB-V）。显微镜检查证实了所描述的宏观发现。对每个阶段枕骨部分的腹背尺寸（LEN）进行了测量。（OB-I至OB-V）阶段与胎龄（AGE）、顶臀长度（CRL）、LEN以及肱骨长度（HL）相关。在OB阶段与枕骨基底部的长度值LEN以及肱骨长度HL之间发现了密切的一致性。在LEN与参数AGE、CRL和HL值之间发现了高度显著的正相关（P < 0.001）。枕骨基底部正常发育的标准被认为对评估颅底产前病理发育很重要。
