Weisz G M, Barzilai A, Assa J, Toledano H
Aust N Z J Surg. 1976 May;46(2):141-7. doi: 10.1111/j.1445-2197.1976.tb03219.x.
The present paper described the technique of intravenous hyperalimentation applied to a group of 100 surgical patients. A specially prepared diet supplying a high amount of calories, using hypertonic glucose and supplying nitrogen, using polypeptides or aminoacid solutions, was infused into the superior vena cava. The inhibition of digestive secretions, during the period of hyperalimentation, was used in the management of 19 patients with intestinal and pancreatic fistulae. The general conclusion reached after wide clinical experience was that by supplying energy and nitrogen to a patient in a severe catabolic state, a significant and sometimes dramatic capacity could be developed which allowed him to overcome difficult conditions and even initiated a reversal of the metabolic balance in the direction of anabolism. The regimen should be adopted in the preoperative preparation of debilitated patients; in hypercatabolic states (post-trauma, post-surgery or burns); in gastrointestinal, granulomatous or infectious diseases; in acute pancreatitis; in digestive fistulae; in oncological conditions, and so on. The metabolic and infective complications can be pregressively decreased and eventually prevented by proper handling and strict metabolic monitoring. The use of this hyperalimentation was extremely encouraging, and on many occasions we had the impression that it was life saving.
本文描述了将静脉高营养技术应用于100例外科患者的情况。一种特制的饮食，通过高渗葡萄糖提供大量热量，通过多肽或氨基酸溶液提供氮，被输注至上腔静脉。在高营养期间，对19例肠瘘和胰瘘患者采用抑制消化液分泌的方法进行治疗。广泛的临床经验得出的总体结论是，通过向处于严重分解代谢状态的患者提供能量和氮，可以显著提高甚至有时戏剧性地提高其能力，使其能够克服困难状况，甚至使代谢平衡朝着合成代谢方向逆转。该疗法应在体弱患者的术前准备中采用；在高分解代谢状态（创伤后、手术后或烧伤后）；在胃肠道、肉芽肿性或感染性疾病中；在急性胰腺炎中；在消化瘘中；在肿瘤疾病等中使用。通过适当处理和严格的代谢监测，可以逐步减少并最终预防代谢和感染并发症。这种高营养的应用非常令人鼓舞，很多时候我们都觉得它能挽救生命。
