Lee J, Jones P H, Trowell J E, Whitear W P, Williams P F
Ipswich Hospital, Suffolk, U.K.
J Infect. 1993 Sep;27(2):181-3. doi: 10.1016/0163-4453(93)94836-z.
We report a case of disseminated histoplasmosis presenting with acute renal impairment due to adrenal insufficiency. The finding of bilateral adrenal gland enlargement on abdominal ultrasound examination led to a diagnostic CT-guided adrenal biopsy. Prolonged therapy with amphotericin and itraconazole resulted in a clinical cure, although the patient still requires adrenal replacement therapy.
我们报告一例播散性组织胞浆菌病,该患者因肾上腺功能不全出现急性肾功能损害。腹部超声检查发现双侧肾上腺增大,遂进行了CT引导下的肾上腺活检。两性霉素和伊曲康唑的长期治疗使患者临床治愈,尽管该患者仍需肾上腺替代治疗。