Kawata T, Kitamura S, Kawachi K, Morita R, Seki T, Taniguchi S, Fukutomi M, Hasegawa J, Kameda Y, Kondo Y
Department of Surgery III, Nara Medical College, Kashihara, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1993 Oct;41(10):2075-80.
Left ventricular function was compared between two groups of patients who underwent patch reconstruction or direct closure of the ventricular wall following resection of a post-infarction left ventricular aneurysm (LVA). There were 15 and 9 patients in the respective groups. Coronary artery bypass grafting was additionally performed in 8 patients (53%) in the patch reconstruction group and 5 patients (56%) in the direct closure group. The size of the patch used for patch reconstruction (including the suture line) was 57 +/- 19% of the resected area. Before and 1-2 months after surgery, equilibrium RI angiography and cardiac catheterization were performed to assess the following hemodynamic parameters: ejection fraction (EF) at rest and during exercise, left ventricular end-diastolic pressure (LVEDP), left ventricular end-diastolic volume index (LVEDVI), cardiac index (CI) and mean pulmonary artery pressure (m-PAP). Preoperatively, there were no differences in each parameter between the two groups. Postoperatively, there were significant improvements in the EF at rest and during exercise (p < 0.01), LVEDVI (p < 0.01) and the LVEDP (p < 0.05). However there no significant changes in CI or m-PAP following the operation. There were also no significant differences observed in the postoperative values between the two groups. However, based upon postoperative left ventriculograms, patch reconstruction was significantly superior to direct closure for reconstruction of a septal aneurysm.
在两组心肌梗死后左心室室壁瘤(LVA)切除术后接受补片重建或直接缝合心室壁的患者之间比较左心室功能。两组分别有15例和9例患者。补片重建组8例患者(53%)和直接缝合组5例患者(56%)还进行了冠状动脉搭桥术。用于补片重建的补片大小(包括缝线)为切除面积的57±19%。在手术前以及术后1至2个月,进行平衡放射性核素血管造影和心导管检查以评估以下血流动力学参数:静息和运动时的射血分数(EF)、左心室舒张末期压力(LVEDP)、左心室舒张末期容积指数(LVEDVI)、心脏指数(CI)和平均肺动脉压(m-PAP)。术前,两组之间各参数无差异。术后,静息和运动时的EF(p<0.01)、LVEDVI(p<0.01)和LVEDP(p<0.05)有显著改善。然而,术后CI或m-PAP无显著变化。两组之间的术后值也未观察到显著差异。然而,根据术后左心室造影,补片重建在重建间隔部室壁瘤方面明显优于直接缝合。